Evaluation and Modeling with the Therapeutic Effects Group
Members
Maîtresse de conférences - praticienne hospitalière
UCBL
Tel: 04 72 11 94 07
Maître de conférences - praticien hospitalier
UCBL
Tel: 33 04 72 32 34 87
Professeur des universités - médecin généraliste
UCBL
Tel: 04 78 74 18 18
Maîtresse de conférences
UCBL
Tel: 33 04 78 78 57 83
Professeure des universités - médecin généraliste
UCBL
Tel: 04 78 77 72 86
Professeur d'université - praticien hospitalier
UCBL
Tel: 04 72 44 81 42
Doctorante
HCL
Assistant hospitalier universitaire
UCBL
Doctorant
UCBL
Tel: 04 72 44 81 42
Professeur d'université - praticien hospitalier
UCBL
Tel: 33 04 72 16 80 99
Doctorante
autre
Tel: 04 72 44 81 42
Praticien hospitalier
HCL
Tel: 04 72 44 81 42
Professeur d'université - praticien hospitalier émérite
UCBL
Professeur d'université - praticien hospitalier
UCBL
Tel: 04 27 85 77 32
Professeur d'université - praticien hospitalier
UCBL
Tel: 33 04 78 86 33 01
Post-doc
UCBL
Maîtresse de conférences - praticienne hospitalière
UCBL
Maître de conférences - praticien hospitalier
UCBL
Tel: 04 72 11 94 20
Doctorante
UCBL
Professeur d'université - praticien hospitalier
UCBL
Tel: 33 04 72 12 94 37
Post-doc
UCBL
Doctorante
UCBL
Tel: 04 72 44 81 42
EMET presentation
The EMET team brings together doctors, pharmacists and research professors specializing in the evaluation and use of drug and non-drug therapies, around a single project built on two axes:
- the evaluation of therapies in clinical trials or observational studies;
- the construction of explanatory and predictive models, to better understand and therefore predict the effect of therapies, simulate their impacts at the individual and population level, and improve the innovation paradigm.
The EMET team is therefore part of two major dynamics in therapy: analysis of the level of evidence and precision medicine.
The fields of application are cardiovascular and metabolic diseases, primary care medicine, rare pediatric diseases (including genetic and autoimmune diseases), oncology and infectious diseases.
EMET members implement approaches using different mathematical models: direct comparison and network meta-analysis, pharmacokinetic/pharmacodynamic analysis, Bayesian networks and machine learning.
Education
The EMET team is specially involved in the teaching of pharmacology and therapeutics and the modeling of the treatment effect through the coordination of the Masters 2 Clinical Evaluation (EC) and Pharmacology modeling and clinical trials (PHAME), Interpretation of Therapeutic Trials (IET), Training of investigators in clinical drug trials (FIEC) and Training of clinical research assistants and clinical study technicians (FARCTEC). Teacher-researchers are also involved in the first (pharmacology), second (pharmacology / therapeutics, pharmacy) and third cycles (general medicine, pediatrics, internal medicine) in health training courses.
Society involvement
The members of the EMET team through their work and their interactions with the other components of the LBBE, National societies, governmental (HAS) or international (EMA) agencies, and the Hospices Civils de Lyon, are invested in current societal issues: rationalization of the use of health product resources, research ethics, gender equality, rationality of approaches in analyzing the diversity of human populations.
Publications
Display of 601 to 613 publications on 613 in total
Systolic and Diastolic Blood Pressure Lowering as Determinants of Cardiovascular Outcome
Hypertension . 45(5) : 907-913
Journal article
see the publicationApparent effect on blood pressure is only partly responsible for the risk reduction due to antihypertensive treatments
Fundamental & Clinical Pharmacology . 19 : 579-584
Journal article
see the publicationModélisation numérique et simulation : nouvelles applications en pharmacologie [New approaches in pharmacology: numerical modelling and simulation]
Thérapie . 60 ( 1 ) : 1-15
Journal article
see the publicationShould age influence the choice of quantitative bone assessment technique in elderly women? The EPIDOS study
Osteoporosis International . 15 : 196-203
Journal article
see the publicationMathematical modelling of an ischemic stroke: an integrative approach.
Acta Biotheoretica . 52 ( 4 ) : 255-72
Journal article
see the publicationA systematic review of the accuracy of ultrasound in the diagnosis of deep venous thrombosis in asymptomatic patients
Thrombosis and Haemostasis . 91 : 655-666
Journal article
see the publicationCausality and statistical association (2) Mechanical determinism and stochastic model
Revue du Praticien (La) . 53 : 933-936
Journal article
see the publicationPrévention de la dépendance des personnes âgées : étude randomisée dans la communauté Prevention of Dependency in Elderly Persons: A Randomised Study in the Community
Thérapie . 89 : 731-9
Journal article
see the publicationHow should therapeutic information be transferred to users?
Fundamental & Clinical Pharmacology . 17 : 495-503
Journal article
see the publicationAbsolute benefit number needed to treat and gain in life expectancy: which efficacy indices for measuring the treatment benefit?
Journal of Clinical Epidemiology . 56 : 977-982
Journal article
see the publicationPharmacogenetics and responders to a therapy: Theoretical background and practical problems
Clinical Chemistry and Laboratory Medicine . 41 : 564-572
Journal article
see the publicationThe assessment of deep vein thromboses for therapeutic trials
Angiology . 54 : 19-24
Journal article
see the publicationLe Projet INDANA : Méta-analyse sur données individuelles des essais cliniques du traitement médicamenteux de l'hypertension artérielle
Thesis
see the publication
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