Statistics and Modelling for Health Sciences
Evaluation and Modeling with the Therapeutic Effects Group
Bourguignon Laurent
Maître de conférences - praticien hospitalier
UCBL
69376 LYON cedex 08
Tel: 33 04 72 32 34 87
Publications
Display of 1 to 30 publications on 43 in total
Evaluation of Renal Impairment Influence on Metabolic Drug Clearance using a Modelling Approach
Clinical Pharmacokinetics . 62 ( 2 ) : 307-319
Journal article
see the publicationMachine-Learning Exploration of Exposure-Effect Relationships of Cisplatin in Head and Neck Cancer Patients
Pharmaceutics . 14 ( 11 ) : 2509
Journal article
see the publicationDaptomycin Physiology-Based Pharmacokinetic Modeling to Predict Drug Exposure and Pharmacodynamics in Skin and Bone Tissues
Clinical Pharmacokinetics . 61 ( 10 ) : 1443-1456
Journal article
see the publicationImplementation of Model-Based Dose Adjustment of Tobramycin in Adult Patients with Cystic Fibrosis
Pharmaceutics . 14 ( 8 ) : 1750
Journal article
see the publicationPopulation Pharmacokinetic Modeling and Dosing Simulations of Tobramycin in Pediatric Patients with Cystic Fibrosis
Antimicrobial Agents and Chemotherapy . 65 ( 10 ) : e0073721
DOI: 10.1128/AAC.00737-21
Journal article
see the publicationModel-Based Comparative Analysis of Rifampicin and Rifabutin Drug-Drug Interaction Profile
Antimicrobial Agents and Chemotherapy . 65 ( 9 ) : e0104321
DOI: 10.1128/AAC.01043-21
Journal article
see the publicationPopulation Pharmacokinetics and Dosing Simulation of Vancomycin Administered by Continuous Injection in Critically Ill Patient
Antibiotics . 10 ( 10 ) : 1228
Journal article
see the publicationDrug interactions between emergency contraceptive drugs and cytochrome inducers: literature review and quantitative prediction
Fundamental & Clinical Pharmacology . 35 ( 2 ) : 208-216
DOI: 10.1111/fcp.12601
Journal article
see the publicationAzithromycin for COVID-19: More Than Just an Antimicrobial?
Clinical Drug Investigation . 40 ( 8 ) : 683-686
Journal article
see the publicationAmikacin Initial Dose in Critically Ill Patients: a Nonparametric Approach To Optimize A Priori Pharmacokinetic/Pharmacodynamic Target Attainments in Individual Patients
Antimicrobial Agents and Chemotherapy . 63 ( 11 ) : e00993-19
DOI: 10.1128/AAC.00993-19
Journal article
see the publicationDeterminants of amikacin first peak concentration in critically ill patients
Fundamental & Clinical Pharmacology .
DOI: 10.1111/fcp.12374
Journal article
see the publicationIs Trough Concentration of Vancomycin Predictive of the Area Under the Curve? A Clinical Study in Elderly Patients
Therapeutic Drug Monitoring . 39 : 83-87
Journal article
see the publicationA Model for Predicting the Interindividual Variability of Drug-Drug Interactions
AAPS Journal . 19 : 497-509
Journal article
see the publicationEvaluation of haemodialysis as a protective technique for preventing high daily dose amikacin nephrotoxicity: an experimental study in an ovine model.
International Journal of Antimicrobial Agents .
Journal article
see the publicationPopulation pharmacokinetics of teicoplanin administered by subcutaneous or intravenous route and simulation of optimal loading dose regimen
Journal of Antimicrobial Chemotherapy . 72 ( 10 ) : 2804-2812
DOI: 10.1093/jac/dkx242
Journal article
see the publicationMechanisms of drug-drug interaction between rifampicin and fusidic acid
British Journal of Clinical Pharmacology . 83 ( 8 ) : 1862-1864
DOI: 10.1111/bcp.13277
Journal article
see the publicationMathematical modeling and systems pharmacology of tuberculosis: Isoniazid as a case study
Journal of Theoretical Biology . 399 : 43-52
Journal article
see the publicationComparison of the static in vivo approach to a physiologically based pharmacokinetic approach for metabolic drug-drug interactions prediction
International Journal of Pharmacokinetics . : 1-10
Journal article
see the publicationA Bayesian Model to Describe Factors Influencing Trough Levels of Vancomycin in Hemodialysis Patients
Nephron Physiology . 131 ( 2 ) : 131-7
DOI: 10.1159/000439230
Journal article
see the publicationPopulation modeling and simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of isoniazid in lungs
Antimicrobial Agents and Chemotherapy . 59 ( 9 ) : 5181-5189
DOI: 10.1128/AAC.00462-15
Journal article
see the publicationInfluence of renal function estimation on pharmacokinetic modeling of vancomycin in elderly patients
Antimicrobial Agents and Chemotherapy . 59 ( 6 ) : 2986-94
DOI: 10.1128/AAC.04132-14
Journal article
see the publicationThe Case for Using Higher Doses of First Line Anti-Tuberculosis Drugs to Optimize Efficacy
Current Pharmaceutical Design . 20 : 6191-6206
Journal article
see the publicationExposure to anticholinergic and sedative drugs, risk of falls, and mortality: an elderly inpatient, multicenter cohort
Journal of clinical psychopharmacology . 34 : 565-70
Journal article
see the publicationPractical application of the charter of pharmaceutical sales visit
Annales Pharmaceutiques Françaises . 70 : 348--52
Journal article
see the publicationIn Vivo Quantitative Prediction of the Effect of Gene Polymorphisms and Drug Interactions on Drug Exposure for CYP2C19 Substrates
AAPS Journal . 15 : 415-26
Journal article
see the publicationBayesian networks: a new method for the modeling of bibliographic knowledge: application to fall risk assessment in geriatric patients
Medical and Biological Engineering and Computing . 51 : 657--64
Journal article
see the publicationCalculation of the first dose of amikacine: evaluation of the current dosage recommendations
Annales Pharmaceutiques Françaises . 71 : 7--12
Journal article
see the publicationVariabilité pharmacocinétique inter- et intra-individuelle lors de traitements par teicoplanine chez les sujets âgés. Inter-individual and intra-individual pharmacokinetic variability during teicoplanin therapy ingeriatric patients
Médecine et Maladies Infectieuses . : 1-4
Journal article
see the publicationComparison of Four Renal Function Estimation Equations for Pharmacokinetic Modeling of Gentamicin in Geriatric Patients
Antimicrobial Agents and Chemotherapy . 56 ( 4 ) : 1862-1869
DOI: 10.1128/AAC.05634-11
Journal article
see the publicationEvaluation of fluoroquinolone reduced dosage regimens in elderly patients by using pharmacokinetic modelling and Monte Carlo simulations
Journal of Antimicrobial Chemotherapy . 67 : 2207--2212
DOI: 10.1093/jac/dks195
Journal article
see the publication