Statistics and Modelling for Health Sciences

Tranexamic acid for epistaxis in hereditary hemorrhagic telangiectasia patients: a European cross-over controlled trial in a rare disease

S. Gaillard, S. Dupuis-Girod, F. Boutitie, S. Riviere, S. Moriniere, P. Y. Hatron...

Journal of Thrombosis and Haemostasis . 12 : 1494-502

DOI: 10.1111/jth.12654

2014

Journal article

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Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions

Fabien Subtil, Muriel Rabilloud

BMC Medical Informatics and Decision Making . 14 : 53

DOI: 10.1186/1472-6947-14-53

2014

Journal article

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Mortality and profiles of community-dwelling fallers. Results from the EPIDOS cohort

S. Bailly, J. Haesebaert, E. Decullier, P. Dargent-Molina, Cédric Annweiler, O. Beauchet...

Maturitas . 79 : 334-9

DOI: 10.1016/j.maturitas.2014.07.017

2014

Journal article

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Real-time Detection of Gastric Insufflation Related to Facemask Pressure-controlled Ventilation Using Ultrasonography of the Antrum and Epigastric Auscultation in Nonparalyzed Patients. A Prospective, Randomized, Double-blind Study

L. Bouvet, Ml. Albert, C. Augris, E. Boselli, René Ecochard, Muriel Rabilloud...

Anesthesiology . 120 : 326-334

DOI: 10.1097/ALN.0000000000000094

2014

Journal article

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Characterization of Prostate lesions as Benign or Malignant at Multiparametric MR imaging: Comparison of Three Scoring Systems in Patients Treated with Radical Prostatectomy

T. Vaché, F. Bratan, F. Mège-Lechevallier, S. Roche, Muriel Rabilloud, O. Rouvière

Radiology . 272 : 446-455

2014

Journal article

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Value of prostate multiparametric magnetic resonance imaging for predicting biopsy results in first or repeat biopsy

H. Habchi, F. Bratan, A. Paye, G. Pagnoux, T. Sanzalone, F. Mege-Lechevallier...

Clinical radiology . 69 : e120-e128

2014

Journal article

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Comparison of an effect-model-law-based method versus traditional clinical practice guidelines for optimal treatment decision-making: application to statin treatment in the French population

R. Kahoul, François Gueyffier, E. Amsallem, M. Haugh, I. Marchant, F. H. Boissel...

Journal of the Royal Society Interface . 11 ( 100 ) : 20140867

DOI: 10.1098/rsif.2014.0867

2014

Journal article

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The effect of methylphenidate on neurofibromatosis type 1: a randomised, double-blind, placebo-controlled, crossover trial

Laurence Lion-François, François Gueyffier, Catherine Mercier, Daniel Gérard, Vania Herbillon, Isabelle Kemlin...

Orphanet Journal of Rare Diseases . 9 : 142

DOI: 10.1186/s13023-014-0142-4

2014

Journal article

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Effects of pharmacological treatments on micro- and macrovascular complications of type 2 diabetes: What is the level of evidence?

R. Boussageon, François Gueyffier, Catherine Cornu

Diabetes & Metabolism . 40 : 169-75

DOI: 10.1016/j.diabet.2013.12.010

2014

Journal article

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Improving risk prediction performance for a better guidelines application

I. Marchant, Theodora Bejan-Angoulvant, Hh. Le, François Gueyffier

Journal of Hypertension . 32 : 1192-1193

DOI: 10.1097/HJH.0000000000000194

2014

Journal article

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The Case for Using Higher Doses of First Line Anti-Tuberculosis Drugs to Optimize Efficacy

Sylvain Goutelle, Laurent Bourguignon, P. Maire, R. W. Jelliffe, M. Neely

Current Pharmaceutical Design . 20 : 6191-6206

2014

Journal article

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Gemcitabine plus cisplatin versus chemoradiotherapy in locally advanced biliary tract cancer: Federation Francophone de Cancerologie Digestive 9902 phase II randomised study

J. M. Phelip, V. Vendrely, F. Rostain, Fabien Subtil, J. L. Jouve, M. Gasmi...

European Journal of Cancer . 50 : 2975-82

2014

Journal article

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Impact of the reduction of calcineurin inhibitors on renal function in heart transplant patients: a systematic review and meta-analysis

Catherine Cornu, C. Dufays, Ségolène Gaillard, François Gueyffier, M. Redonnet, Laurent Sebbag...

British Journal of Clinical Pharmacology . 78 ( 1 ) : 24-32

DOI: 10.1111/bcp.12289

2014

Journal article

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Number needed to treat from absolute risk and incidence rate: how to make apples and oranges comparable?

N. Girerd, Muriel Rabilloud, K. Duarte, Pascal Roy

Journal of Clinical Epidemiology . 67 ( 2 ) : 236-238

DOI: 10.1016/j.jclinepi.2013.08.010

2014

Journal article

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Creatinine- versus cystatine C-based equations in assessing the renal function of candidates for liver transplantation with cirrhosis

V. de Souza, A. Hadj-Aissa, O. Dolomanova, Muriel Rabilloud, N. Rognant, Sandrine Lemoine...

Hepatology . 59 ( 4 ) : 1522-31

DOI: 10.1002/hep.26886

2014

Journal article

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Impact of vitamin D supplementation on health-care use in a 25-hydroxyvitamin D-tested population in France: a population-based descriptive cohort study

Pascal Caillet, Susan B Jaglal, L. Laforest, Roland Chapurlat, Muriel Rabilloud, Michel Ducher...

Public Health Nutrition . : 1--11

DOI: 10.1017/S136898001400038X

2014

Journal article

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A stepped wedge cluster randomized trial is preferable for assessing complex health interventions

M. Keriel-Gascou, K. Buchet-Poyau, Muriel Rabilloud, A. Duclos, C. Colin

Journal of Clinical Epidemiology . 67 : 831-833

2014

Journal article

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Frequency, causes and risk factors of postpartum haemorrhage: a population-based study in 106 French maternity units

C. Dupont, R. C. Rudigoz, M. Cortet, S. Touzet, C. Colin, Muriel Rabilloud...

Journal de Gynécologie Obstétrique et Biologie de la Reproduction . 43 : 244-53

DOI: 10.1016/j.jgyn.2013.05.003

2014

Journal article

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Improvement of sample size calculations for binary diagnostic test assessment

S. Bailly, C. Dupont, J. Iwaz, Nadine Bossard, Muriel Rabilloud

Journal of investigative medicine . 62 : 687-9

DOI: 10.231/JIM.0000000000000066

2014

Journal article

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A pyriform sinus cancer organ preservation strategy comprising induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil, followed by potentiated radiotherapy: a multicenter, retrospective study

P. Ceruse, A. Cosmidis, A. Belot, Muriel Rabilloud, C. Fuchsmann, M. Poupart...

Anti-cancer Drugs . 25 : 970-5

DOI: 10.1097/CAD.0000000000000126

2014

Journal article

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Cardiovascular Events and Bleeding Risk Associated With Intravitreal Antivascular Endothelial Growth Factor Monoclonal Antibodies: Systematic Review and Meta-analysis

M. Thulliez, D. Angoulvant, M. L. Le Lez, Annie-Pierre Jonville-Bera, P. J. Pisella, François Gueyffier...

JAMA Ophthalmology . 132 ( 11 ) : 1317-26

DOI: 10.1001/jamaophthalmol.2014.2333

2014

Journal article

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Guidelines for Managing High Blood Pressure

Dk. Cundiff, François Gueyffier, Jm. Wright

Journal of the American Medical Association . 312 ( 3 ) : 293-294

DOI: 10.1001/jama.2014.6590

2014

Journal article

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Multivariate meta-analysis using individual participant data

R. D. Riley, M. J. Price, D. Jackson, M. Wardle, François Gueyffier, J. Wang...

Research Synthesis Methods . 6 ( 2 ) : 157-174

DOI: 10.1002/jrsm.1129

2014

Journal article

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Can we identify response markers to antihypertensive drugs? First results from the Ideal Trial.

Gueyffier F., Subtil F., Bejan-Angoulvant T., Yves Zerbib, Baguet Jp, Boivin Jm...

Journal of Human Hypertension . : doi: 10.1038/jhh.2014.29

2014

Journal article

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Determinants of torsades de pointes in older patients with drug-associated long QT syndrome: a case-control study

Sylvain Goutelle, E. Sidolle, M. Ducher, J. Caron, Q. Timour, Patrice Nony...

Drugs & aging . 31 : 601-9

2014

Journal article

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Exposure to anticholinergic and sedative drugs, risk of falls, and mortality: an elderly inpatient, multicenter cohort

V. Dauphinot, R. Faure, S. Omrani, Sylvain Goutelle, Laurent Bourguignon, P. Krolak-Salmon...

Journal of clinical psychopharmacology . 34 : 565-70

DOI: 10.1097/JCP.0000000000000195

2014

Journal article

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Pharmacokinetic Drug Interaction Between Cyclosporine and Imatinib in Bone Marrow Transplant Children and Model-Based Reappraisal of Imatinib Drug Interaction Profile

Nathalie Bleyzac, K. Kebaili, V. Mialou, Y. Bertrand, Sylvain Goutelle

Therapeutic Drug Monitoring . 36 : 724-729

2014

Journal article

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Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children

E. Bernard, Sylvain Goutelle, Y. Bertrand, Nathalie Bleyzac

The Annals of Pharmacotherapy . 48 : 1580-4

DOI: 10.1177/1060028014550644

2014

Journal article

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Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial

J. Taieb, J. Tabernero, E. Mini, Fabien Subtil, G. Folprecht, Jl. van Laethem...

Lancet Oncology . 15 : 862-873

2014

Journal article

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Modeling the seasonality of Anopheles gambiae s.s. biting rates in a South Benin sanitary zone

O. Boussari, Fabien Subtil, N. Moiroux, A. Djenontin, J. Iwaz, V. Corbel...

Transactions of The Royal Society of Tropical Medicine and Hygiene . 108 : 237-43

DOI: 10.1093/trstmh/tru027

2014

Journal article

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Statistics and Modelling for Health Sciences

Biostatistics Health Group

Evaluation and Modeling with the Therapeutic Effects Group

Publications

Tranexamic acid for epistaxis in hereditary hemorrhagic telangiectasia patients: a European cross-over controlled trial in a rare disease

Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions

Mortality and profiles of community-dwelling fallers. Results from the EPIDOS cohort

Real-time Detection of Gastric Insufflation Related to Facemask Pressure-controlled Ventilation Using Ultrasonography of the Antrum and Epigastric Auscultation in Nonparalyzed Patients. A Prospective, Randomized, Double-blind Study

Characterization of Prostate lesions as Benign or Malignant at Multiparametric MR imaging: Comparison of Three Scoring Systems in Patients Treated with Radical Prostatectomy

Value of prostate multiparametric magnetic resonance imaging for predicting biopsy results in first or repeat biopsy

Comparison of an effect-model-law-based method versus traditional clinical practice guidelines for optimal treatment decision-making: application to statin treatment in the French population

The effect of methylphenidate on neurofibromatosis type 1: a randomised, double-blind, placebo-controlled, crossover trial

Effects of pharmacological treatments on micro- and macrovascular complications of type 2 diabetes: What is the level of evidence?

Improving risk prediction performance for a better guidelines application

The Case for Using Higher Doses of First Line Anti-Tuberculosis Drugs to Optimize Efficacy

Gemcitabine plus cisplatin versus chemoradiotherapy in locally advanced biliary tract cancer: Federation Francophone de Cancerologie Digestive 9902 phase II randomised study

Impact of the reduction of calcineurin inhibitors on renal function in heart transplant patients: a systematic review and meta-analysis

Number needed to treat from absolute risk and incidence rate: how to make apples and oranges comparable?

Creatinine- versus cystatine C-based equations in assessing the renal function of candidates for liver transplantation with cirrhosis

Impact of vitamin D supplementation on health-care use in a 25-hydroxyvitamin D-tested population in France: a population-based descriptive cohort study

A stepped wedge cluster randomized trial is preferable for assessing complex health interventions

Frequency, causes and risk factors of postpartum haemorrhage: a population-based study in 106 French maternity units

Improvement of sample size calculations for binary diagnostic test assessment

A pyriform sinus cancer organ preservation strategy comprising induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil, followed by potentiated radiotherapy: a multicenter, retrospective study

Cardiovascular Events and Bleeding Risk Associated With Intravitreal Antivascular Endothelial Growth Factor Monoclonal Antibodies: Systematic Review and Meta-analysis

Guidelines for Managing High Blood Pressure

Multivariate meta-analysis using individual participant data

Can we identify response markers to antihypertensive drugs? First results from the Ideal Trial.

Determinants of torsades de pointes in older patients with drug-associated long QT syndrome: a case-control study

Exposure to anticholinergic and sedative drugs, risk of falls, and mortality: an elderly inpatient, multicenter cohort

Pharmacokinetic Drug Interaction Between Cyclosporine and Imatinib in Bone Marrow Transplant Children and Model-Based Reappraisal of Imatinib Drug Interaction Profile

Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children

Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial

Modeling the seasonality of Anopheles gambiae s.s. biting rates in a South Benin sanitary zone

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