Statistics and Modelling for Health Sciences

Estimation and Short-Term Prediction of the Course of the HIV Epidemic Using Demographic and Health Survey Methodology-Like Data

S. Blaizot, B. Riche, D. Maman, I. Mukui, B. Kirubi, Jf. Etard...

PLoS ONE . 10 ( 6 ) : e0130387

DOI: 10.1371/journal.pone.0130387

2015

Journal article

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Sweat test practice in pediatric pulmonology after introduction of cystic fibrosis newborn screening

Céline Grimaldi, François Brémont, Michèle Berlioz-Baudoin, Jacques Brouard, Harriet Corvol, Laure Couderc...

European Journal of Pediatrics . 174 ( 12 ) : 1613 - 1620

DOI: 10.1007/s00431-015-2579-4

2015

Journal article

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An impulse oscillometry system is less efficient than spirometry in tracking lung function improvements after intravenous antibiotic therapy in pediatric patients with cystic fibrosis

Clélia Buchs, Laurianne Coutier, Stéphanie Vrielynck, Virginie Jubin, Catherine Mainguy, Philippe Reix

Pediatric Pulmonology . 50 ( 11 ) : 1073 - 1081

DOI: 10.1002/ppul.23301

2015

Journal article

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A French multicentric study and review of pulmonary Nocardia spp. in cystic fibrosis patients

Véronica Rodriguez-Nava, Stéphane Durupt, Sandra Chyderiotis, Anne-Marie Freydiere, Judith Karsenty, Michèle de Montclos...

Medical Microbiology and Immunology . 204 ( 4 ) : 493-504

DOI: 10.1007/s00430-014-0360-3

2015

Journal article

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Idiopathic inflammatory myopathies and the lung

Jean-Christophe Lega, Quitterie Reynaud, Alexandre Belot, Nicole Fabien, Isabelle Durieu, Vincent Cottin

European Respiratory Review . 24 ( 136 ) : 216-238

DOI: 10.1183/16000617.00002015

2015

Journal article

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Evaluation of Early Reperfusion Criteria in Acute Ischemic Stroke

B. Ozenne, Th. Cho, Ik. Mikkelsen, M. Hermier, L. Ribe, G. Thomalla...

Journal of Neuroimaging . 25 : 952-8

DOI: 10.1111/jon.12255

2015

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Assessing the benefit-risk of new treatments using generalised pairwise comparisons: the case of erlotinib in pancreatic cancer

Julien Peron, Pascal Roy, K. Ding, W. R. Parulekar, L. Roche, M. Buyse

Breast Cancer Research and Treatment . 112 ( 6 ) : 971-6

DOI: 10.1038/bjc.2015.55

2015

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Severity of post-partum hemorrhage after vaginal delivery is not predictable from clinical variables available at the time post-partum hemorrhage is diagnosed

Marion Cortet, Delphine Maucort-Boulch, Catherine Deneux-Tharaux, Corinne Dupont, René-Charles Rudigoz, Pascal Roy...

Journal of Obstetrics and Gynaecology Research . 41 ( 2 ) : 199-206

DOI: 10.1111/jog.12528

2015

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Predicting Corneal Graft Rejection by Confocal Microscopy

V. Kocaba, C. Colica, Muriel Rabilloud, C. Burillon

Cornea . 34 : S61-4

2015

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An enhancement of ROC curves made them clinically relevant for diagnostic-test comparison and optimal-threshold determination

Fabien Subtil, Muriel Rabilloud

Journal of Clinical Epidemiology . 68 : 752-9

DOI: 10.1016/j.jclinepi.2015.01.003

2015

Journal article

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Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study

C. Vale, L. Rydzewska, M. Rovers, J. Emberson, François Gueyffier, L. Stewart

British medical journal . 350 : h1088

DOI: 10.1136/bmj.h1088

2015

Journal article

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Subcutaneous administration of levetiracetam in geriatrics

O. Maison, B. de La Gastine, L. Peter-Derex, C. Berger, Sylvain Goutelle

Revue Neurologique . 171 : 398-399

2015

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A pharmacometric pulmonary model predicting the extent and rate of distribution from plasma to epithelial lining fluid and alveolar cells-using rifampicin as an example

O. Clewe, Sylvain Goutelle, Jr. Conte, Ush. Simonsson

European Journal of Clinical Pharmacology . 71 ( 3 ) : 313-9

DOI: 10.1007/s00228-014-1798-3

2015

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Quantitative methods for prediction of the effect of cytochrome P450 gene polymorphisms on substrate drug exposure

Sylvain Goutelle, M. Tod

Clinical Pharmacokinetics . 54 : 319-20

2015

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Model-Based Determination of Effective Blood Concentrations of Cyclosporine for Neutrophil Response in the Treatment of Severe Aplastic Anemia in Children

M. Philippe, E. Henin, Y. Bertrand, D. Plantaz, Sylvain Goutelle, N. Bleyzac

AAPS Journal . 17 ( 5 ) : 1157-67

DOI: 10.1208/s12248-015-9779-8

2015

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Population modeling and simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of isoniazid in lungs

Laure Lalande, Laurent Bourguignon, S. Bihari, P. Maire, M. Neely, R. Jelliffe...

Antimicrobial Agents and Chemotherapy . 59 ( 9 ) : 5181-5189

DOI: 10.1128/AAC.00462-15

2015

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The precision–recall curve overcame the optimism of the receiver operating characteristic curve in rare diseases

Brice Ozenne, Fabien Subtil, Delphine Maucort-Boulch

Journal of Clinical Epidemiology . 68 : 855-9

2015

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Spatially regularized mixture model for lesion segmentation with application to stroke patients

B. Ozenne, Fabien Subtil, L. Ostergaard, Delphine Maucort-Boulch

Biostatistics . 16 ( 3 ) : 580-595

DOI: 10.1093/biostatistics/kxv004

2015

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An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

S. Blein, Claire Bardel, V. Danjean, L. Mcguffog, S. Healey, D. Barrowdale...

Breast Cancer Research . 17 : 61

DOI: 10.1186/s13058-015-0567-2

2015

Journal article

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Management of adolescents with very poorly controlled type 1 diabetes by nurses: a parallel group randomized controlled trial

B. Kassai, Muriel Rabilloud, D. Bernoux, C. Michal, B. Riche, T. Ginhoux...

Trials . 16 ( 1 ) : 399

DOI: 10.1186/s13063-015-0923-7

2015

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Comparison of two next-generation sequencing kits for diagnosis of epileptic disorders with a user-friendly tool for displaying gene coverage, DeCovA

S. Dimassi, T. Simonet, A. Labalme, N. Boutry-Kryza, Amandine Campan-Fournier, R. Lamy...

Applied & Translational Genomics . 7 : 19-25

DOI: 10.1016/j.atg.2015.10.001

2015

Journal article

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Accuracy of different equations in estimating GFR in pediatric kidney transplant recipients

V. de Souza, P. Cochat, Muriel Rabilloud, L. Selistre, M. Wagner, A. Hadj-Aissa...

Clinical Journal of the American Society of Nephrology . 10 ( 3 ) : 463-70

DOI: 10.2215/CJN.06300614

2015

Journal article

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Clinical profile of patients with ATP1A3 mutations in Alternating Hemiplegia of Childhood-a study of 155 patients

E. Panagiotakaki, E. de Grandis, M. Stagnaro, E. L. Heinzen, C. Fons, S. Sisodiya...

Orphanet Journal of Rare Diseases . 10 : 123

DOI: 10.1186/s13023-015-0335-5

2015

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Influence of renal function estimation on pharmacokinetic modeling of vancomycin in elderly patients

A. Glatard, Laurent Bourguignon, R. W. Jelliffe, P. Maire, M. N. Neely, Sylvain Goutelle

Antimicrobial Agents and Chemotherapy . 59 ( 6 ) : 2986-94

DOI: 10.1128/AAC.04132-14

2015

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CSF IgA NMDAR antibodies are potential biomarkers for teratomas in anti-NMDAR encephalitis

V. Desestret, A. Chefdeville, A. Viaccoz, C. Bost, F. Ducray, G. Picard...

Neurology Neuroimmunology & Neuroinflammation . 2 ( 6 ) : e166

DOI: 10.1212/NXI.0000000000000166

2015

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An 18F-FDG-PET maximum standardized uptake value > 10 represents a novel valid marker for discerning Richter’s Syndrome

Anne-Sophie Michallet, Pierre Sesques, Kari Rabe, Emmanuel Itti, Jérémy Tordot, Christelle Tychyj-Pinel...

Leukemia & lymphoma . 57 ( 6 ) : 1474-1477

DOI: 10.3109/10428194.2015.1099643

2015

Journal article

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Different treatment benefits were estimated by clinical trials performed in adults compared with those performed in children

Perrine Janiaud, A. Lajoinie, F. Cour-Andlauer, Catherine Cornu, P. Cochat, Michel Cucherat...

Journal of Clinical Epidemiology . 68 : 1221-1231

2015

Journal article

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Is legacy a myth or a reality? We should know, and we do not

F. Gueyffier, Michel Cucherat

Journal of Hypertension . 33 : 2207-9

2015

Journal article

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Sequential combination of gemcitabine, vinorelbine, pegylated liposomal doxorubicin and Brentuximab as a bridge regimen to transplant in relapsed or refractory Hodgkin lymphoma

As. Michallet, Y. Guillermin, B. Deau, L. Lebras, S. Harel, S. Amorin...

Haematologica . 100 ( 7 ) : e269-e271

DOI: 10.3324/haematol.2015.124784

2015

Journal article

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High Risk versus Proportional Benefit: Modelling Equitable Strategies in Cardiovascular Prevention

I. Marchant, Jp. Boissel, Patrice Nony, F. Gueyffier

PLoS ONE . 10 ( 11 ) : e0140793

DOI: 10.1371/journal.pone.0140793

2015

Journal article

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Statistics and Modelling for Health Sciences

Biostatistics Health Group

Evaluation and Modeling with the Therapeutic Effects Group

Publications

Estimation and Short-Term Prediction of the Course of the HIV Epidemic Using Demographic and Health Survey Methodology-Like Data

Sweat test practice in pediatric pulmonology after introduction of cystic fibrosis newborn screening

An impulse oscillometry system is less efficient than spirometry in tracking lung function improvements after intravenous antibiotic therapy in pediatric patients with cystic fibrosis

A French multicentric study and review of pulmonary Nocardia spp. in cystic fibrosis patients

Idiopathic inflammatory myopathies and the lung

Evaluation of Early Reperfusion Criteria in Acute Ischemic Stroke

Assessing the benefit-risk of new treatments using generalised pairwise comparisons: the case of erlotinib in pancreatic cancer

Severity of post-partum hemorrhage after vaginal delivery is not predictable from clinical variables available at the time post-partum hemorrhage is diagnosed

Predicting Corneal Graft Rejection by Confocal Microscopy

An enhancement of ROC curves made them clinically relevant for diagnostic-test comparison and optimal-threshold determination

Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study

Subcutaneous administration of levetiracetam in geriatrics

A pharmacometric pulmonary model predicting the extent and rate of distribution from plasma to epithelial lining fluid and alveolar cells-using rifampicin as an example

Quantitative methods for prediction of the effect of cytochrome P450 gene polymorphisms on substrate drug exposure

Model-Based Determination of Effective Blood Concentrations of Cyclosporine for Neutrophil Response in the Treatment of Severe Aplastic Anemia in Children

Population modeling and simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of isoniazid in lungs

The precision–recall curve overcame the optimism of the receiver operating characteristic curve in rare diseases

Spatially regularized mixture model for lesion segmentation with application to stroke patients

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

Management of adolescents with very poorly controlled type 1 diabetes by nurses: a parallel group randomized controlled trial

Comparison of two next-generation sequencing kits for diagnosis of epileptic disorders with a user-friendly tool for displaying gene coverage, DeCovA

Accuracy of different equations in estimating GFR in pediatric kidney transplant recipients

Clinical profile of patients with ATP1A3 mutations in Alternating Hemiplegia of Childhood-a study of 155 patients

Influence of renal function estimation on pharmacokinetic modeling of vancomycin in elderly patients

CSF IgA NMDAR antibodies are potential biomarkers for teratomas in anti-NMDAR encephalitis

An 18F-FDG-PET maximum standardized uptake value > 10 represents a novel valid marker for discerning Richter’s Syndrome

Different treatment benefits were estimated by clinical trials performed in adults compared with those performed in children

Is legacy a myth or a reality? We should know, and we do not

Sequential combination of gemcitabine, vinorelbine, pegylated liposomal doxorubicin and Brentuximab as a bridge regimen to transplant in relapsed or refractory Hodgkin lymphoma

High Risk versus Proportional Benefit: Modelling Equitable Strategies in Cardiovascular Prevention

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