Quantitative and Evolutionary Ecology of Communities Group
Delignette-Muller Marie-Laure
Professeure des universités
VetAgro-Sup
Tel: 33 04 72 43 27 56
I am a Professor at VetAgro Sup, responsible for various modules of biostatistics at the veterinary curriculum, a module of critical reading of articles and co-leader of a module of Bayesian statistics mutualized between the three masters piloted by the LBBE. Some of my teaching documents are available on my personal web page.
My research activity is in the field of biometrics. I develop models and inference methods in the context of risk assessment in the field of health and environmental risks. My objective is to propose models/methods useful to researchers to better understand risks, and useful to managers to define risk indicators. My areas of expertise are: hierarchical models, non-linear models, dose-response models, in particular dose-response modeling of omics data, Bayesian inference.
In order to facilitate the use of the methods I develop to the largest number of people, I am involved in the development of various R packages: fitdistrplus, nlstools, DRomics.
My publications are listed exhaustively on my Google Scholar profile and my most recent papers are available on my HAL CV.
Publications
Display of 31 to 60 publications on 123 in total
Evaluation using latent class models of the diagnostic performances of three ELISA tests commercialized for the serological diagnosis of Coxiella burnetii infection in domestic ruminants
Gemeinsamen Arbeitstagung der Nationalen Referenzlabore Chlamydiose, Q-Fieber, Paratuberkulose und Tuberkulose der Rinder - Online-Tagung veranstaltet . : 17 slides
Conference paper
see the publicationEvaluation using latent class models of the diagnostic performances of three ELISA tests commercialized for the serological diagnosis of Coxiella burnetii infection in domestic ruminants
Veterinary Research . 52 ( 1 )
Journal article
see the publicationPhenotypic and Transcriptomic Responses to Stress Differ According to Population Geography in an Invasive Species
Genome Biology and Evolution . 13 ( 9 ) : evab208
DOI: 10.1093/gbe/evab208
Journal article
see the publicationEvaluation, à l’aide de modèles à classes latentes, des performances diagnostic des tests ELISA commercialisés pour le diagnostic sérologique des infections par Coxiella burnetii chez les ruminants domestiques
17ème Rencontre des Microbiologistes du Pôle Clermontois .
Conference paper
see the publicationModelling for risk assessment
Journées du LIEC : l’interdisciplinarité au service de l’environnement .
Conference paper
see the publicationDevelopmental variability channels mouse molar evolution
eLife . 9 ( 27 )
DOI: 10.7554/eLife.50103
Journal article
see the publicationA multi-omics concentration-response framework uncovers novel understanding of triclosan effects in the chlorophyte Scenedesmus vacuolatus
Journal of Hazardous Materials . 397 : 122727
Journal article
see the publicationDevelopmental variability channels mouse molar evolution
eLife .
DOI: 10.7554/eLife.50103
Journal article
see the publicationEffect of interspecific competition on species sensitivity distribution models: Analysis of plant responses to chemical stress
Ecotoxicology and Environmental Safety . 200 : 110722
Journal article
see the publicationUtilisation de DRomics pour modéliser les données omiques de type dose-réponse dans le cadre de l’appréciation du risque environnemental
SEFA (Société d’Ecotoxicologie Fondamentale et Appliquée) .
Conference paper
see the publicationSome issues about the design of preclinical trials
Séminaire Celphedia (Création, ELevage, PHEnotypage, DIstribution et Archivage d'organismes modèles) .
Conference paper
see the publicationDRomics: an R tool for modelling omics dose-response data
Congrès useR! .
Poster
see the publicationComparison of the effect of alfaxalone VS medetomidine and ketamine for induction of anaesthesia in Trachemys scripta sp. undergoing sterilisation
Joint Leibniz-IZW/EAZWV/ECZM Zoo and Wildlife Health Conference .
Conference paper
see the publicationCombination of prior distributions elicited from expert opinions previous to Bayesian inference. Application to personalized medicine
Bayes 2019 (Bayesian Biostatistics conference) .
Conference paper
see the publicationAssessment of diagnostic tests in the absence of a gold standard: a Bayesian approach simultaneously using latent class and mixture models for the diagnosis of bovine dictyocaulosis
BAYES2019 Lyon: Bayesian Biostatistics .
Conference paper
see the publicationApproche de Modélisation Hiérarchique pour la Description de l'Effet de la Compétition Interspécifique sur la Tolérance Chimique d'Herbacées
SEFA 2019 Lyon .
Conference paper
see the publicationOutils d'observation des boiteries
Journées Nationales des Groupements Techniques Vétérinaires (JNGTV) . : np
Poster
see the publicationImportance de la variabilité intraspécifique de la polluosensibilité pour l’évaluation du risque ecotoxicologique basée sur l’approche SSD (Species Sensitivity Distribution)
38ème colloque de l’Association des Diatomistes de Langue Française (ADLaF) .
Conference paper
see the publicationModelling of omics dose-response data for ecological risk assessment
Journées du GDR Ecologie Statistique (EcoStat) .
Conference paper
see the publicationNew goodness-of-fit plots for censored data in the package fitdistrplus
7ème rencontres R .
Conference paper
see the publicationHow to implement functional responses of migroalgae in risk assessment processing ?
Congrès européen de la SETAC «Science and Technology for Environmental Protection» .
Conference paper
see the publicationDefining simple toxicity values (EC, BMD) is not so simple
Congrès européen de la SETAC «Science and Technology for Environmental Protection» .
Poster
see the publicationDiagnosis of bovine dictyocaulosis by bronchoalveolar lavage technique: A comparative study using a Bayesian approach
Preventive Veterinary Medicine . 154 : 124-131
Journal article
see the publicationEvaluation de méthodes diagnostiques en l’absence de gold standard sur la base de variables binaires et continues : intérêt de l'approche bayésienne
Journée AppliBUGS . : 38 slides
Conference paper
see the publicationMOSAIC: a web-interface for statistical analyses in ecotoxicology
Environmental Science and Pollution Research . 25 ( 12 ) : 11295-11302
Journal article
see the publicationDRomics: A Turnkey Tool to Support the Use of the Dose–Response Framework for Omics Data in Ecological Risk Assessment
Environmental Science and Technology . 52 ( 24 ) : 14461-14468
Journal article
see the publicationAssessment of Ozone or Not-Treated Wastewater Ecotoxicity Using Mechanism-Based and Zebrafish Embryo Bioassays
Journal of Environmental Protection . 09 ( 04 ) : 325 - 346
Journal article
see the publicationResponse to Comment on "Robust Fit of Toxicokinetic-Toxicodynamic Models Using Prior Knowledge Contained in the Design of Survival Toxicity Tests
Environmental Science and Technology . 51 : 8202-8203
Journal article
see the publicationRobust Fit of Toxicokinetic-Toxicodynamic Models Using Prior Knowledge Contained in the Design of Survival Toxicity Tests
Environmental Science and Technology . 51 : 4038-4045
Journal article
see the publicationAnalysis of hemocytes in Lymnaea stagnalis: Characterization and effects of repeated hemolymph collections
Fish and Shellfish Immunology . 57 : 116-126
Journal article
see the publication