COEVOL Multi-Scale Coevolution

Evolutionary Genetics of Interactions Group

The Cocoon Group

Living systems are highly integrated, with a multitude of levels of organization, from molecular and intra-cellular scales to ecosystems. Complex organisms are themselves consortia of macro- and micro-organisms, which work together with their host to build the individual. Yet, each of these organisms can function and evolve in the short term according to its own logic, possibly in conflict with other higher or lower levels, or with other time scales. The once common idea among evolutionists that natural selection results in organisms perfectly adapted to their environment is now severely undermined. Not only because, as the Red Queen explains to Alice, one has to run relentlessly to keep its place in a changing environment, or because past evolutionary history and chance constrain the possibilities of present adaptation, but also because different levels of selection have interests that are generally difficult to reconcile.

Multi-scale coevolution resets classical questions in evolutionary biology

One example, of particular interest is the question of the source of heritable variations. The phenotype of organisms in a population is influenced not only by variations in their nuclear and mitochondrial genomes, the dynamics of which is the object of population genetics, but also more and more patently by the consortium of microbes and genetic elements that constitute its microbiome and virome. The hologenome designates this complex assembly of genetic materials, which obey different rules of transmission and different evolutionary strategies. The ability of symbionts to manipulate host phenotypes or to interfere with each other influences the evolutionary dynamics of all players in ways that are yet poorly understood. In addition, new questions arise, such as the importance of co-adaptation in these systems and their consequences in maintaining cohesive biological systems.

  •  Symbiosis: a response to and a source of divergent selection

Using a variety of approaches combining experimental evolution, genomic, functional, phenotypic and behavioral data, we aim to test whether symbiosis facilitates diversification and to characterize the underlying microevolutionary processes.

  •  Ecological networks of horizontal gene transfer

We develop original methods to detect gene transfer and we investigate the factors that influence the routes of gene transfers among microbes but also among insects.

  •  The interplay between symbiosis, infection and immunity and its evolutionary consequences

We try to understand the intimate interaction of hosts with pathogens, symbionts and transposable elements and how it affects the extended phenotype of the host.

  • Transgenerational inheritance and environment changes

We try to decipher the molecular mechanisms that underlie rapid adaptation to environment and to test for transgenerational inheritance of fitness traits.

  •  Intragenomic conflicts and demography

We are developing models to test whether changes in the demography of the host affect the dynamics of transposable elements.

  • The determinism of phenotypic convergence

We study the genomic basis of convergent phenotypic evolution in particular in the case of animals and plants adaptation to increasing temperature and decreasing water.

  • Reconciling the tree of life

We develop phylogenetic methods for “reconciling” gene/species or host/symbiont histories and use these methods to explore the bulk of extinct or undescribed species and the history of association of symbiotic microbes with their hosts.

Integrating methods

The methods we use to tackle the questions raised by multi-scale co-evolution extend from theory, modelling and simulation to big data analysis, lab (notably on insects), and to a lesser extent, field activities.

Implication of research, responsibility of researchers and citizen sciences

From our research (some of which have immediate consequences in health, agriculture and ecology) and our concerns about the responsibility of scientists in society, we are committed to promote an “implicative” research. The implicative position means that we try to work on the link between science and society, not only through a one-way communication, applying or explaining our science, but also favoring early discussions on research projects, that may influence our research directions.

Publications

Display of 601 to 630 publications on 768 in total

The evolution of retrotransposon regulatory regions and its consequences on the Drosophila melanogaster and Homo sapiens host genomes

Marie Fablet, Rita Rebollo, Christian Biémont, Cristina Vieira

Gene . 390 ( 1-2 ) : 84-91

DOI: 10.1016/j.gene.2006.08.005

Journal article

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Behavioural manipulation of insect parasitoids by a maternally inherited virus: ecological consequences and potential applications for biological control

Julien Varaldi, S. Patot, M. Maache, D. Lepetit, Frédéric Fleury

Entomological Research . 37 : A11-A73

Journal article

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Evolution and invasion dynamics of multiple infections with Wolbachia investigated using matrix based models.

E. Vautrin, Sandrine Charles, S. Genieys, F. Vavre

Journal of Theoretical Biology . 245 : 197-209

Journal article

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Parasitic inhibition of cell death facilitates symbiosis.

Bart A Pannebakker, Benjamin Loppin, Coen P H Elemans, Lionel Humblot, Fabrice Vavre

Proceedings of the National Academy of Sciences of the United States of America . 104 ( 1 ) : 213-5

DOI: 10.1073/pnas.0607845104

Journal article

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Tomato yellow leaf curl virus transmission efficacy is determined by symbiotic bacteria in the vector the sweet potato whitefly Bemisia tabaci

E. Zchori-Fein, Y.. Gottlieb, H. Czosnek, E. Chiel, F. Vavre, Frédéric Fleury...

Entomological Research . 37(1) : A42-A43

Journal article

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A Survey of the Bacteriophage WO in the Endosymbiotic Bacteria Wolbachia

L. Gavotte, H. Henri, R. Stouthamer, D. Charif, S. Charlat, M. Boulétreau...

Molecular Biology and Evolution . 24 : 427-435

Journal article

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Variable-Number Tandem Repeats as Molecular Markers for Biotypes of Pasteuria ramosa in Daphnia spp

L. Mouton, G. Nong, J.F. Preston, D. Ebert

Applied and Environmental Microbiology . 73 : 3715-3718

Journal article

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Evolutionary Pathways of the tirant LTR Retrotransposon in the Drosophila melanogaster Subgroup of Species

M. Fablet, S. Souames, C. Biémont, Cristina Vieira

Journal of Molecular Evolution . 64 : 438-447

Journal article

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Male-killing bacteria trigger a cycle of increasing male fatigue and female promiscuity

S. Charlat, M. Reuter, E.A. Dyson, E.A. Hornett, A. Duplouy, N. Davies...

Current Biology . 17 : 273-277

Journal article

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Male rarity and putative sex-role reversal in Fijian damselflies (Odonata)

H. van Gossum, C.D. Beatty, S. Charlat, H. Waqa, T. Markwell, J.H. Skevington...

Journal of Tropical Ecology . 23 : 591-598

Journal article

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The solution space of sorting by reversals

Marília D.V. Braga, Marie-France Sagot, Celine Scornavacca, Eric Tannier

3rd International Symposium on Bioinformatics Research and Applications (ISBRA 2007) . 4463 : 293-304

DOI: 10.1007/978-3-540-72031-7_27

Conference paper

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Evolution under Reversals: Parsimony and Conservation of Common Intervals

Y. Diekmann, M.-F. Sagot, Eric Tannier

IEEE/ACM Transactions on Computational Biology and Bioinformatics . 4 : 301-309

Journal article

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Advances on sorting by reversals

Eric Tannier, A. Bergeron, M.-F. Sagot

Discrete Applied Mathematics . 155 : 881-888

Journal article

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Théorie des Codes : compression, cryptage, correction

Jean-Guillaume Dumas, Jean-Louis Roch, Eric Tannier, Sébastien Varrette

9782100506927 : 352

Book

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Grinding up wheat: A massive loss of nucleotide diversity since domestication

Annabelle Haudry, Alberto Cenci, C. Ravel, Thomas Bataillon, Dominique Brunel, C. Poncet...

Molecular Biology and Evolution . 24 ( 7 ) : 1506-1517

DOI: 10.1093/molbev/msm077

Journal article

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The effects of age at mating on female life-history traits in a seed beetle

A.A. Maklakov, N. Kremer, G. Arnqvist

Behavioral Ecology . 18 : 551-555

Journal article

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Horizontal Gene Transfer Regulation in Bacteria as a ‘‘Spandrel'' of DNA Repair Mechanisms

Saliou Fall, Anne Mercier, Franck Bertolla, Alexandra Calteau, Laurent Gueguen, Guy Perrière...

PLoS ONE . 2 ( 10 ) : e1055-e1066

DOI: 10.1371/journal.pone.0001055

Journal article

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MareyMap: an R-based tool with graphical interface for estimating recombination rates

C. Rezvoy, D. Charif, Laurent Guéguen, Gabriel Marais

Bioinformatics . 23 : 2188-2189

Journal article

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The Sublethal Effects of Pesticides on Beneficial Arthropods

N. Desneux, A. Decourtye, Jean-Marie Delpuech

Annual Review of Entomology . 52 : 81-106

Journal article

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Interaction between host genotype and environmental conditions affects bacterial density in Wolbachia symbiosis

L. Mouton, H. Henri, D. Charif, M. Boulétreau, F. Vavre

Biology Letters . 3 : 210-213

Journal article

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Reverse Arrangement of rRNA Subunits in the Microsporidium Glugoides intestinalis

D. Refardt, L. Mouton

Journal of Eukaryotic Microbiology . 54 : 83-85

Journal article

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Insertion polymorphism of transposable elements and population structure of Anopheles gambiae M and S molecular forms in Cameroon

M. Boulesteix, F. Simard, C. Antonio-Nkondjio, P. Awono-Ambene, D. Fontenille, C. Biémont

Molecular Ecology . 16 : 441-452

Journal article

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Disrupting the timing of Wolbachia-induced male-killing

S. Charlat, N. Davies, G.K. Roderick, G.D. Hurst

Biology Letters . 3 : 154-156

Journal article

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Extraordinary flux in sex ratio

Sylvain Charlat, Emily Hornett, James Fullard, Neil Davies, George Roderick, Nina Wedell...

Science . 317 ( 5835 ) : 214-214

DOI: 10.1126/science.1143369

Journal article

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When can host shifts produce congruent host and parasite phylogenies? A simulation approach

Damien M de Vienne, Tatiana Giraud, J A Shykoff

Journal of Evolutionary Biology . 20 ( 4 ) : 1428--1438

Journal article

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Comparative genomics and the evolution of prokaryotes

Sophie S. Abby, Vincent Daubin

Trends in Microbiology . 15 : 135-141

Journal article

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Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography

Philippe Normand, Pascal Lapierre, Louis S. Tisa, Johann Peter Gogarten, Nicole Alloisio, Emilie Bagnarol...

Genome Research . 17 : 7-15

DOI: 10.1101/gr.5798407

Journal article

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Grinding up wheat: a massive loss of nucleotide diversity since domestication

A. Haudry, A. Cenci, C. Ravel, T. Bataillon, D. Brunel, C. Poncet...

Molecular Biology and Evolution . 24 : 1506-1517

Journal article

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Mitspieler der Evolution

C. Biémont, Cristina Vieira

Spektrum der Wissenschaft . S44 : 44-49

Journal article

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