COEVOL Multi-Scale Coevolution

Evolutionary Genetics of Interactions Group

Vavre Fabrice

Directeur de recherche

CNRS

Address: 43 bd du 11 novembre 1918
69622 VILLEURBANNE cedex

Tel: 33 04 72 43 19 21

Email

Who am we? Who are I?

These two strange questions perfectly define my research interests. I study interspecific relationships, anotably symbiotic interactions, using as a model the interactions between arthropods and bacteria with mainly vertical transmission (from mother to offspring). The objective is to understand the dynamics of this chimeric individual, the factors that orient these interactions towards conflict or cooperation, and their consequences on the extended phenotype of the individual and the evolution of each of the partners. The subtlety of these interactions, which continually navigate between selfish and shared interests, is particularly important to consider and integrate into the trendy study of the holobiont and the microbiota. This general theme is currently structured around 3 main projects:

Co-adaptation within holobionts. Within the framework of the ANR Hmicmac project, we are seeking, with Laurence Mouton, to test the hypothesis that host-microbiota interactions should lead to co-adaptation between partners. This hypothesis is tested using experimental evolution based on situations where these possible co-adaptations are initially broken and then left free to evolve again. This approach is being carried out on the whitefly Bemisia tabaci and its symbiotic bacteria at the LBBE, and will be compared with similar experiments carried out on the pea aphid. This project also involves the IGEPP (Rennes) and BF2I (Lyon) laboratories.

Response of symbioses to stress. Within the framework of the RESIST project (ANR JCJC, coord. Natacha Kremer, LBBE), we are seeking to test whether symbiosis is a driving force or a barrier to adaptation to new environmental stresses. We are using the association between Drosophila melanogaster and Wolbachia (wMelPop strain), which is subjected to punctual or chronic stresses with either a pro-oxidant agent (the herbicide paraquat), or virus C, or both simultaneously.

Dynamics of obligate symbiotic interactions in ticks.  Within the framework of the MICROM project (ANR, coord. O. Duron, MIVEGEC), we are seeking to understand the whys and wherefores of recurrent replacements of obligate nutritional symbionts in ticks. Indeed, these strict haematophagous arthropods depend on nutritional symbionts providing them with B vitamins. However, multiple replacement events have occurred during tick evolution. Future work at the LBBE will be dedicated to comparative genomics of symbionts from different tick species.

Finally, within the framework of several projects (SBP MicroBeHave, 2 CIFRE theses, an ANR and a project), we have developed with Julien Varaldi and Natacha Kremer, in collaboration with the BF2I laboratory and the company Izinovation, a new project on  bedbugs, a re-emerging pest due to its resistance to insecticides, strictly haematophagous and totally dependent on symbionts of the Wolbachia genus for the supply of B vitamins. Our work seeks to characterise the genetic mechanisms of resistance and to better understand the genetic and metabolic dialogue between the insect and its symbiont.

Development of "One Health" approaches in Lyon

In addition to these scientific aspects, I am also involved in the construction of the research ecosystem in Lyon  on One Health approaches. This has led me to lead the Symbiotron platform project for more than 10 years, and since 2021 to coordinate the recently funded Equipex+ Infectiotron project led by the University of Lyon 1. This project seeks to develop a set of coordinated tools for the operational development of projects on infectious diseases from their natural environment to the laboratory, with a particular focus on level 3 pathogens. I am also actively involved in the implementation and development of the SHAPE-Med@Lyon project, also led by the University of Lyon 1, and in particular for the development of the Lyon Transdisciplinary Health Institute.

Publications

Display of 31 to 60 publications on 101 in total

Parasite-Parasite Interactions in the Wild: How To Detect Them?

Eléonore Hellard, David Fouchet, Fabrice Vavre, Dominique Pontier

Trends in Parasitology .

Journal article

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Spodoptera frugiperda (Lepidoptera: Noctuidae) host-plant variants: two host strains or two distinct species?

Pascaline Dumas, Fabrice Legeai, Claire Lemaitre, Erwan Scaon, Marion Orsucci, Karine Labadie...

Genetica . 143 ( 3 ) : 305-316

DOI: 10.1007/s10709-015-9829-2

Journal article

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The Genome of Cardinium cBtQ1 Provides Insights into Genome Reduction, Symbiont Motility, and Its Settlement in Bemisia tabaci

Diego Santos-Garcia, Pierre-Antoine Rollat-Farnier, Francisco Beitia, Einat Zchori-Fein, Fabrice Vavre, Laurence Mouton...

Genome Biology and Evolution . 6 ( 4 ) : 1013-1030

DOI: 10.1093/gbe/evu077

Journal article

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Signs of Neutralization in a Redundant Gene Involved in Homologous Recombination in Wolbachia Endosymbionts

Myriam Badawi, Isabelle Giraud, Fabrice Vavre, Pierre Grève, Richard Cordaux

Genome Biology and Evolution . 10 ( 6 ) : 2654-2664

DOI: 10.1093/gbe/evu207

Journal article

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Manipulation of arthropod sex determination by endosymbionts: diversity and molecular mechanisms

Wen-Juan Ma, Fabrice Vavre, Leo W. Beukeboom

Sexual Development . : 59-73

Journal article

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Microbial impacts on insect evolutionary diversification: from patterns to mechanisms

Fabrice Vavre, Natacha Kremer

Current Opinion in Insect Science . 4 : 29--34

DOI: 10.1016/j.cois.2014.08.003

Journal article

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Epidemiology of asexuality induced by the endosymbiotic Wolbachia across phytophagous wasp species: host plant specialization matters.

Thomas Boivin, Hélène Henri, Fabrice Vavre, Cindy Gidoin, Philippe Veber, Jean-Noël Candau...

Molecular Ecology Notes . 23 ( 9 ) : 2362-2375

DOI: 10.1111/mec.12737

Journal article

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The Genome of Cardinium cBtQ1 Provides Insights into Genome Reduction, Symbiont Motility, and Its Settlement in Bemisia tabaci

Diego Santos-Garcia, Pierre-Antoine Rollat-Farnier, Francisco Beitia, Einat Zchori-Fein, Fabrice Vavre, Laurence Mouton...

Genome Biology and Evolution . 6 ( 4 ) : 1013-1030

Journal article

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Distribution of endosymbiotic reproductive manipulators reflects invasion process and not reproductive system polymorphism in the little fire ant Wasmannia auropunctata

Olivier REY, Arnaud Estoup, Benoit Facon, Anne Loiseau, Alexandre Aebi, Olivier Duron...

PLoS ONE . 8 ( 3 ) : e58467

DOI: 10.1371/journal.pone.0058467

Journal article

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Distribution of Bemisia tabaci (Homoptera: Aleyrodidae) biotypes and their associated symbiotic bacteria on host plants in West Africa

Olivier Gnankine, Laurence Mouton, Hélène Henri, Gabriel Terraz, Thomas Houndeté, Thibaud Martin...

Insect conservation and diversity . 6 ( 3 ) : 411 - 421

DOI: 10.1111/j.1752-4598.2012.00206.x

Journal article

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Endosymbiont diversity among sibling weevil species competing for the same resource

Adrien Merville, Samuel Venner, Hélène Henri, Agnès Vallier, Frédéric Menu, Fabrice Vavre...

BMC Evolutionary Biology . 13 : 28

DOI: 10.1186/1471-2148-13-28

Journal article

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Interactions et rétroactions : rôle de leur écologie et de leur évolution dans le fonctionnement des écosystèmes.

J. Roy, D. Bouchon, Dov Corenblit, Thierry Dutoit, F. Lallier, N. Niquil...

Prospectives de l’Institut Ecologie et Environnement du CNRS .

Book chapter

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Biotype status and resistance to neonicotinoids and carbosulfan in Bemisia tabaci (Hemiptera: Aleyrodidae) in Burkina Faso, West Africa

Olivier Gnankine, Laurence Mouton, Aly Savadogo, Thibaud Martin, Antoine Sanon, Roch Dabiré...

International Journal of Pest Management . 59 ( 2 ) : 95-102

DOI: 10.1080/09670874.2013.771806

Journal article

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Influence of the virus LbFV and of Wolbachia in a host-parasitoid interaction.

Julien Martinez, Anne Duplouy, Megan Woolfit, Fabrice Vavre, Scott L O'Neill, Julien Varaldi

PLoS ONE . 7 ( 4 ) : 1-10

DOI: 10.1371/journal.pone.0035081

Journal article

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Complete Genome Sequence of "Candidatus Portiera aleyrodidarum" BT-QVLC, an Obligate Symbiont That Supplies Amino Acids and Carotenoids to Bemisia tabaci.

Diego Santos-Garcia, Pierre-Antoine Farnier, Francisco Beitia, Einat Zchori-Fein, Fabrice Vavre, Laurence Mouton...

Journal of Bacteriology . 194 ( 23 ) : 6654-6655

DOI: 10.1128/JB.01793-12

Journal article

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Evolution and control of host-microbe symbiosis in arthropods: an RNAseq-based transcriptomic analysis

Yves Moné, F. Chevalier, M.C. Carpentier, N. Kremer, Patrick Mavingui, V. Raquin...

7. International Wolbachia conference . 978-2-911320-44-6

Conference paper

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Influence of Wolbachia on host gene expression in an obligatory symbiosis.

Natacha Kremer, Delphine Charif, Hélène Henri, Frédérick F. Gavory, Patrick Wincker, Patrick Mavingui...

BMC Microbiology . 12 ( Suppl 1 ) : 1-16

DOI: 10.1186/1471-2180-12-S1-S7

Journal article

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Does a parthenogenesis-inducing Wolbachia induce vestigial cytoplasmic incompatibility?

Ken Kraaijeveld, Barbara M Reumer, Laurence Mouton, Natacha Kremer, Fabrice Vavre, Jacques J.M. van Alphen

The Science of Nature Naturwissenschaften . 98 ( 3 ) : 175-80

DOI: 10.1007/s00114-010-0756-x

Journal article

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RNA-seq without a reference genome: a comparison of the mapping and the assembly approaches

M.-C. Carpentier, J. Charif, Vincent Lacroix, Marie-France Sagot, Fabrice Vavre

JOBIM .

Conference paper

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Bacterial symbionts in insects or the story of communities affecting communities.

Julia Ferrari, Fabrice Vavre

Philosophical Transactions of the Royal Society B: Biological Sciences . 366 ( 1569 ) : 1389-400

DOI: 10.1098/rstb.2010.0226

Journal article

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Intraspecific specialization of the generalist parasitoid Cotesia sesamiae revealed by polyDNAvirus polymorphism and associated with different Wolbachia infection.

Antoine Branca, Bruno Pierre Le Ru, Fabrice Vavre, Jean-François Silvain, Stéphane Dupas

Molecular Ecology . 20 ( 5 ) : 959-71

DOI: 10.1111/j.1365-294X.2010.04977.x

Journal article

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Endosymbionts of arthropods and nematodes: allies to fight infectious diseases?

Fabrice Vavre, Patrick Mavingui

Médecine/Sciences . 27 ( 11 ) : 953-958

DOI: 10.1051/medsci/20112711010

Journal article

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Do variable compensatory mechanisms explain the polymorphism of the dependence phenotype in the Asobara tabida-wolbachia association?

Natacha Kremer, Franck Dedeine, Delphine Charif, Cédric Finet, Roland Allemand, Fabrice Vavre

Evolution - International Journal of Organic Evolution . 64 ( 10 ) : 2969-79

DOI: 10.1111/j.1558-5646.2010.01034.x

Journal article

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The transmission efficiency of tomato yellow leaf curl virus by the whitefly Bemisia tabaci is correlated with the presence of a specific symbiotic bacterium species.

Yuval Gottlieb, Einat Zchori-Fein, Netta Mozes-Daube, Svetlana Kontsedalov, Marisa Skaljac, Marina Brumin...

Journal of Virology . 84 ( 18 ) : 9310-7

DOI: 10.1128/JVI.00423-10

Journal article

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Endosymbiont metacommunities, mtDNA diversity and the evolution of the Bemisia tabaci (Hemiptera: Aleyrodidae) species complex.

Gwénaelle Gueguen, Fabrice Vavre, Olivier Gnankine, Michel Peterschmitt, Delphine Charif, Elad Chiel...

Molecular Ecology . 19 ( 19 ) : 4365-4378

DOI: 10.1111/j.1365-294X.2010.04775.x

Journal article

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Évolution des interactions entre espèces

Thierry Lefèvre, François Renaud, Marc-André Selosse, Frédéric Thomas, C. Bernstein, O. Broennimann...

Biologie évolutive . : 533-616

Book chapter

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Intragenomic conflict in populations infected by Parthenogenesis Inducing Wolbachia ends with irreversible loss of sexual reproduction.

Richard Stouthamer, James E Russell, Fabrice Vavre, Leonard Nunney

BMC Evolutionary Biology . 10 : 229

DOI: 10.1186/1471-2148-10-229

Journal article

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A new case of Wolbachia dependence in the genus Asobara: evidence for parthenogenesis induction in Asobara japonica

N. Kremer, D. Charif, H. Henri, M. Bataille, G. Prévost, K. Kraaijeveld...

Heredity . 103 ( 3 ) : 248-256

DOI: 10.1038/hdy.2009.63

Journal article

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Molecular detection and identification of Rickettsia endosymbiont in different biotypes of Bemisia tabaci

G. Gueguen, Jean-Marc Rolain, E. Zchori-Fein, F. Vavre, Frédéric Fleury, Didier Raoult

Clinical Microbiology and Infection . -- : 1-2

Journal article

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